Thalidomide is a notorious drug that caused horrific birth defects in the 1950s, though its damage in the U.S. was limited by Dr. Frances Oldham Kelsey and the FDA. Now, thalidomide has found a different use in the field of targeted protein degradation as part of a new class of therapeutics.
Continue ReadingScientists recently discovered a new peptide that inhibits a disease-protein by recruiting it to an intracellular protein shredder. This peptide shows proof of concept for a potential class of drugs that act by degrading misbehaving proteins in the body.
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